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Dual role of AP-2γ in ErbB-2-induced mammary tumorigenesis

✍ Scribed by Richard Jäger; Nicolaus Friedrichs; Inge Heim; Reinhard Büttner; Hubert Schorle

Book ID: 106376728
Publisher: Springer US
Year: 2005
Tongue: English
Weight: 380 KB
Volume: 90
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-004-4815-x

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## Abstract Loss of heterozygosity (LOH) at human chromosome bands 1p32–36 and 10q23–26 is frequent in various human tumors, including breast cancers, and is thought to reflect the loss of tumor‐suppressor genes (TSGs). To map such genes, high‐resolution LOH analysis was performed on 93 __Erbb2__‐i