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Dual Role for Escherichia coli RecA Protein in SOS Mutagenesis

✍ Scribed by Don G. Ennis, Belva Fisher, Susan Edmiston and David W. Mount

Book ID
123631875
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
830 KB
Volume
82
Category
Article
ISSN
0027-8424

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We examined the possibility that the recA441 mutation, which partially suppresses the UV sensitivity of uvr recF mutant bacteria, exerts its effect by coding for an altered RecA protein that competes more efficiently than the RecA+ protein with SSB for ssDNA in vivo. Using an assay measuring recombi