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Dual regulation of renal Kir7.1 potassium channels by protein Kinase A and protein Kinase C

✍ Scribed by Wei Zhang; Edgar Zitron; Ramona Bloehs; Sandra Müller-Krebs; Eberhard Scholz; Martin Zeier; Hugo Katus; Christoph Karle; Vedat Schwenger

Book ID
116297665
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
836 KB
Volume
377
Category
Article
ISSN
0006-291X

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Exposure of non-excitatory cells to the tyrosine kinase (PTK) inhibitors, genistein, herbimycin A, and tyrphostin, induced at least two families of K f currents. The first, a TEA-insensitive slow-inactivating K + current, is induced within 3 min following treatment with 140 m M genistein or 100 n M