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Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation

✍ Scribed by Nicolas Fissolo; Marianne Kraus; Michael Reich; Miriam Ayturan; Herman Overkleeft; Christoph Driessen; Robert Weissert


Book ID
102163345
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
231 KB
Volume
38
Category
Article
ISSN
0014-2980

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## Abstract Cytokines and chemokines govern leukocyte trafficking, thus regulating inflammatory responses. In this study, the anti‐inflammatory effects of low dose 17β‐estradiol were evaluated on chemokine, chemokine receptor, and cytokine expression in the spinal cords (SC) of BV8S2 transgenic fem