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Dual inhibition of Cdc20 by the spindle checkpoint

โœ Scribed by Rey-Huei Chen

Book ID
106577062
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
215 KB
Volume
14
Category
Article
ISSN
1021-7770

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## Abstract Cdc20, an activator of the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase, initiates the destruction of key mitotic regulators to facilitate mitosis, while it is negatively regulated by the spindle assembly checkpoint (SAC) to prevent premature anaphase entry. Activation