Dual immunocytochemical staining of receptors for oestrogen (ER) and epidermal growth factor (EGFR) in human breast cancer
โ Scribed by Sharma, AK; Horgan, K; Douglas-Jones, AG; McClelland, RA; Nicholson, RI
- Book ID
- 122870473
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 53 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0960-9776
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A new dual immunocytochemical assay for oestrogen receptor (ER) and epidermal growth factor receptor (EGFR) has been developed. It has been tested in a variety of conditions using cell culture lines and the results correlate well with those obtained from single immunocytochemical assays. MCF-7 and
Proteins regulated by or related to the oestrogen receptor (ER) may prove to be more reliable indicators of prognosis and hormone sensitivity then expression of the receptor itself. It has been shown recently that expression of epidermal growth factor receptor (EGFR) is associated with a poor progno