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Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence

✍ Scribed by Tomoyuki Mizuno; Kohta Mohri; Shiho Nasu; Kazumi Danjo; Hirokazu Okamoto

Book ID
113692657
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
420 KB
Volume
134
Category
Article
ISSN
0168-3659

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## Abstract ## Background Dry powder dispersion devices offer potential for delivering therapeutic macromolecules to the pulmonary epithelia. Previously, freeze‐drying (lyophilisation) has been the accepted method for preparing dried formulations of proteins and non‐viral gene vectors despite the