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Dual functions for transcriptional regulators: Myth or reality?

✍ Scribed by René St-Arnaud


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
133 KB
Volume
75
Category
Article
ISSN
0730-2312

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✦ Synopsis


Several transcriptional regulatory molecules have been described that appear to possess dual function in separate cellular compartments. It remains unclear whether the proteins really exert dual functions, or which of the transcriptional regulatory role or the cytoplasm-associated function is the physiologically relevant action of the protein. This review will briefly describe the cases at hand and attempt to sort the true bifunctional proteins from the aritfactual trespassers.


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