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Dual Function C-Terminal Domain of Dynamin-1: Modulation of Self-Assembly by Interaction of the Assembly Site with SH3 Domains †

✍ Scribed by Scaife, Robin; Vénien-Bryan, Catherine; Margolis, Robert L.


Book ID
126289849
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
136 KB
Volume
37
Category
Article
ISSN
0006-2960

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C-terminal SH3 domain of CrkII regulates
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## Abstract Genetic studies in __Caenorhabiditis elegans__ identified an evolutionarily conserved CED‐2 (CrkII), CED‐5 (DOCK180), CED‐12 (ELMO), CED‐10 (Rac1) module important for cell migration and phagocytosis of apoptotic cells. Previous studies have shown that DOCK180 and ELMO comprise an uncon