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Dual effects of sodium butyrate on hepatocellular carcinoma cells

✍ Scribed by Wenjun Jiang; Qiya Guo; Jun Wu; Bin Guo; Yingming Wang; Shenan Zhao; Huiling Lou; Xin Yu; Xinyu Mei; Chaoqun Wu; Shouyi Qiao; Yanhua Wu

Book ID
113075922
Publisher
Springer
Year
2012
Tongue
English
Weight
519 KB
Volume
39
Category
Article
ISSN
0301-4851

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Suppression of growth of hepatocellular
Suppression of growth of hepatocellular carcinoma by sodium butyrate in vitro and in vivo
✍ Hidenao Yamamoto; Jiro Fujimoto; Eizo Okamoto; Jun-ichi Furuyama; Taiki Tamaoki; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 146 KB πŸ‘ 1 views

Treatment of HuH-7 human hepatocellular carcinoma (HCC) cells with 1-10 mM sodium butyrate (SB) resulted in growth inhibition in a dose-dependent manner. At 3 mM and higher concentrations, SB caused nuclear fragmentation and DNA ladder formation characteristic of apoptosis. In the treated cells, the