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Dual effect of (−)-N6-phenylisopropyl adenosine on guinea-pig trachea

✍ Scribed by L. Caparrotta; F. Cillo; G. Fassina; R.M. Gaion

Book ID
117958105
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
853 KB
Volume
83
Category
Article
ISSN
0007-1188

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Stereoselective behavioral effects of N6
Stereoselective behavioral effects of N6-phenylisopropyl-adenosine and antagonism by caffeine
✍ Steven R. Goldberg; José A. Prada; Jonathan L. Katz 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 663 KB

Effects of the (-)- and (+)-isomers of N6-(phenylisopropyl)-adenosine (PIA) were studied in rats trained to respond under fixed-interval and fixed-ratio schedules of food reinforcement. Both isomers of PIA decreased response rates; however, the (-)-isomer decreased response rates at doses as low as