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Dual cholinergic modulation of hippocampal somatic and dendritic field potentials by the septo-hippocampal pathway

✍ Scribed by C. Rovira; Y. Ben-Ari; E. Cherubini


Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
380 KB
Volume
49
Category
Article
ISSN
0014-4819

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✦ Synopsis


In rats under urethane anaesthesia, brief tetanic stimulation of the medial septum produces a dual effect upon the field potentials elicited in the ammon's horn by commissural stimulation: a facilitation of the population spike recorded in the pyramidal layer and a depression of the field EPSP recorded in the apical dendrites. Both effects, which are also produced by local application of muscarinic agents, are antagonized by local administration of muscarinic antagonists.