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Dual actions of viomycin on the ribosomal functions

โœ Scribed by Yei-Fei Liou; Nobuo Tanaka

Book ID
118310902
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
387 KB
Volume
71
Category
Article
ISSN
0006-291X

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โœ Yamada, Takeshi ;Nierhaus, Knud H. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer ๐ŸŒ English โš– 356 KB

The peptide antibiotic viomycin at a concentration of 10 muM inhibits E. coli ribosomes to the extent of about 70% as measured in the poly (U) system, and to about 85% in a natural mRNA (R17) system. Ribosomes from M. smegmatis show no activity at all at this concentration of the antibiotic. Experim