Drugs targeting integrins for cancer therapy
β Scribed by Binder, Mascha; Trepel, Martin
- Book ID
- 126903466
- Publisher
- Informa plc
- Year
- 2009
- Tongue
- English
- Weight
- 876 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1746-0441
No coin nor oath required. For personal study only.
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## Abstract Antiβangiogenesis is a promising strategy for the treatment of cancer. Integrins, consisting of two noncovalently bound transmembrane Ξ± and Ξ² subunits, are an important molecular family involved in tumor angiogenesis. The blockade of integrin signaling has been demonstrated to be effici
Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed