Drug–DNA interaction: A theoretical study on the binding of thionine with DNAs of varying base composition
✍ Scribed by Yunus, G.; Srivastava, S.; Kuddus, M.; Gupta, V.D.
- Book ID
- 120820278
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 404 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1567-1739
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a Collection Of Useful Molecular Techniques To Illuminate And Explore The Interaction Of Drugs And Ligands With Dna. These Easily Reproducible Methods Involve Sequence Recognition Properties, As Well As The Physical Approaches For Measuring Both The Strength Of Interaction And The Mode Of Drug Bindi
Diffusion of DAPI (4",6-diamidino-2-phenylindole) to its DNA binding site d(AATT) is simulated by Brownian dynamics. The simulations are performed on all atom x-ray structures of the molecules with systematic intermolecular forces and hydrodynamic interactions. The roles of hydrodynamic and intermo