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Drug transport in corneal epithelium and blood–retina barrier: Emerging role of transporters in ocular pharmacokinetics

✍ Scribed by Eliisa Mannermaa; Kati-Sisko Vellonen; Arto Urtti

Book ID
113418065
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
685 KB
Volume
58
Category
Article
ISSN
0169-409X

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## Abstract ## Aims The objective of the present study was to evaluate drug efflux transporter interactions of darifenacin and examine the impact of such transporter interactions on darifenacin permeability in an __in vitro__ model of the blood–brain barrier (BBB) and blood–ocular barrier (BOB).