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Drug testing in animals for teratogenic effects: Thalidomide in the pregnant rat

✍ Scribed by Robert L. Brent

Book ID
118533871
Publisher
Elsevier Science
Year
1964
Tongue
English
Weight
684 KB
Volume
64
Category
Article
ISSN
1097-6833

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Mercuric mercury (Hg2+), like cadmium (Cd2+), interferes with the transport of certain essential metals to the conceptus in the pregnant Wistar rat and, at 48 h after the IV injection of a teratogenic dose (0.79 mg Hg2+/kg body weight) on day 12 of gestation, the foetal concentrations of Zn2+, Cu2+