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Drug survival rates for tumour necrosis factor-α antagonists in psoriasis

✍ Scribed by A.D. Burden

Book ID: 108671756
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 43 KB
Volume: 164
Category: Article
ISSN: 0007-0963
DOI: 10.1111/j.1365-2133.2011.10355.x

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## Abstract The biological effects of tumour necrosis factor (TNF)-α are mediated through either the TNFR1 or the TNFR2 receptor. In the present study, the effects of ultraviolet (UV) irradiation on skin pathology and tumour promotion were studied in hairless mice deficient in either the TNFR1 or t