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Drug Resistance and Heterogeneous Long-Term Virologic Responses of Human Immunodeficiency Virus Type 1-Infected Subjects to Zidovudine and Didanosine Combination Therapy

โœ Scribed by Shafer, R. W.; Iversen, A. K. N.; Winters, M. A.; Aguiniga, E.; Katzenstein, D. A.; Merigan, T. C.


Book ID
121402071
Publisher
University of Chicago Press
Year
1995
Tongue
English
Weight
831 KB
Volume
172
Category
Article
ISSN
0022-1899

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## Abstract An assay for the analysis of point mutations in DNA fragments amplified by the polymerase chain reaction is described. The method was applied to the analysis of mutations leading to single amino acid changes in the reverse transcriptase gene of human immunodeficiency virus typeโ€1 that a