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Drug Metabolism: Renal Excretion of Rhodamine 123, a P-Glycoprotein Substrate, in Rats with Glycerol-induced Acute Renal Failure

โœ Scribed by MASAHIRO KUNIHARA; JUNYA NAGAI; TERUO MURAKAMI; MIKIHISA TAKANO

Book ID
118111125
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
532 KB
Volume
50
Category
Article
ISSN
2042-7158

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Comparative study on altered hepatic met
Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure
โœ Jun-ichi Kusaba; Noriko Kajikawa; Hiromu Kawasaki; Yuji Kurosaki; Tetsuya Aiba ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 147 KB ๐Ÿ‘ 2 views

To examine the mechanism accounting for the diverse alteration of hepatic metabolism of CYP3A substrates observed with renal function being severely impaired, the hepatic drug metabolizing activity was evaluated using liver microsomes prepared from rats with glycerol-induced acute renal failure (ARF