The effects of dose on the pharmacokinetic characteristics of KNI-272 were evaluated in rats after intravenous (iv) administration. The plasma kinetics of KNI-272 were dose-independent within a dose range of 1.0 to 10.0 mg/kg. However, when the dose was increased to 50.0 mg/kg, the area under the pl
Drug interactions between HIV protease inhibitors based on physiologically-based pharmacokinetic model
β Scribed by Nobuhito Shibata; Weihua Gao; Hiroyuki Okamoto; Tomoyuki Kishida; Koji Iwasaki; Yukako Yoshikawa; Kanji Takada
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 135 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0022-3549
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