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Drug-induced oxidative stress in rat liver from a toxicogenomics perspective

✍ Scribed by Michael McMillian; Alex Nie; J. Brandon Parker; Angelique Leone; Michael Kemmerer; Stewart Bryant; Judy Herlich; Lynn Yieh; Anton Bittner; Xuejun Liu; Jackson Wan; Mark D. Johnson; Peter Lord

Book ID
113923655
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
564 KB
Volume
207
Category
Article
ISSN
0041-008X

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## Abstract Cholestasis, encountered in a variety of clinical disorders, is characterized by intracellular accumulation of toxic bile acids in the liver. Furthermore, oxidative stress plays an important role in the pathogenesis of bile acids. Taurolithocholic acid (TLC) was revealed in previous stu