Liver-specific and proliferation-induced
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Mary Ann Crissey; Julia I. Leu; Robert A. De Angelis; Linda E. Greenbaum; L. Mar
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Article
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1999
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John Wiley and Sons
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English
⚖ 423 KB
The insulin-like growth factor binding protein-1 (IGFBP-1) gene is highly expressed in fetal, perinatal, and regenerating liver. Up-regulation is transcriptionally mediated in regenerating liver and occurs in the first few minutes to hours after partial hepatectomy. In transgenic mice a 970-bp regio