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Drug-induced Liver Disease || Role of the Adaptive Immune System in Idiosyncratic Drug-Induced Liver Injury

✍ Scribed by Uetrecht, Jack


Book ID
120328694
Publisher
Elsevier
Year
2013
Weight
558 KB
Category
Article
ISBN
0123878179

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Drug-induced idiosyncratic liver disease (DIILD) depends largely on host susceptibility factors. Small studies support the genetic influence of human leukocyte antigen (HLA) class II molecules on the predisposition to DIILD. We sought associations between HLA-DRB and -DQB alleles and DIILD considere