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Drug-Induced Changes in the Liver Endoplasmic Reticulum: Association with Drug-Metabolizing Enzymes

✍ Scribed by Remmer, H.; Merker, H. J.


Book ID
121171056
Publisher
American Association for the Advancement of Science
Year
1963
Tongue
English
Weight
594 KB
Volume
142
Category
Article
ISSN
0036-8075

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Postmortem changes in the drug-metabolizing enzymes in rat liver microsome were studied. Parameters investigated were: microsomal protein, NADPH-cytochrome P-450 reductase activity, NADH-cytochrome b5 reductase activity, cytochrome b5 content, cytochrome P-450 content, aminopyrine N-demethylase acti