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Drug-induced changes in renal hippurate clearance as a measure of renal blood flow

✍ Scribed by Visscher, C Antoinette; de Zeeuw, Dick; de Jong, Paul E; Sluiter, Wim J; Huisman, Roel M

Book ID
109884232
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
591 KB
Volume
48
Category
Article
ISSN
0085-2538

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Changes in renal clearance of furosemide
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We have shown that, within therapeutic plasma concentrations, the unbound fraction of furosemide changes in direct proportion to the reciprocal of the plasma albumin concentration (correlation coefficient 0.99). Changes in the albumin concentration were produced by ultrafiltration of human plasma us