This Book Offers Readers An Array Of New Emerging Technologies. These Technologies Arm Pharmaceutical Scientists With More Systematic And Effective Approaches For Deciphering The Complex Interactions Among Chemstry, Biology, And Medicine, Helping To Ensure That More Research Efforts Focus On Drugs That Can Be Successfully Translated From The Laboratory To The Clinic And Onto The Market.--jacket. Focus On The Fundamentals : Toward Better Therapeutic Index Prediction / Jinghai J. Xu And Li J. Yu -- High-throughput Protein-based Technologies And Computational Models For Drug Development, Efficacy, And Toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, And Christopher W. Espelin -- Cellular Systems Biology Applied To Preclinical Safety Testing : A Case Study Of Cellciphr Profiling / Lawrence Vernetti ... [et Al.] -- Systems Pharmacology, Biomarkers, And Biomolecular Networks / Aram S. Adourian ... [et Al.] -- Zebrafish Models For Human Diseases And Drug Discovery / Hanbing Zhong, Ning-ai Liu, And Shuo Lin -- Toxicity Pathways And Models : Mining For Potential Side Effects / Sean Ekins And Josef Scheiber -- Computational Systems Biology Modeling Of Dosimetry And Cellular Response Pathways / Qiang Zhang ... [et Al.] -- Stem Cell Technology For Embryotoxicity, Cardiotoxicity, And Hepatotoxicity Evaluation / Julio C. Davila ... [et Al.] -- Telemetry Technology For Preclinical Drug Discovery And Development / Yi Yang --nanotechnology To Improve Oral Drug Delivery / Mayank D. Bhavsar, Shardool Jain, And Mansoor M. Amiji -- Functional Glycomics And The Future Of Glycomic Drugs / Ram Sasisekharan And Karthik Viswanathan -- Modeling Efficacy And Safety Of Engineered Biologics / Jeffrey R. Chabot And Bruce Gomes -- Regulation Of Gene Expression By Small, Non-coding Rnas : Practical Applications / Roman Herrara And Eric Tien -- Future Perspectives Of Biological Engineering In Pharmaceutical Research : The Paradigm Of Modeling, Mining, Manipulation, And Measurements / Jinghai J. Xu ... [et Al.]. [edited By] Sean Ekins, Jinghai J. Xu. Includes Bibliographical References And Index.