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Drug distribution in the head, axillary and pubic hair of chronic addicts

✍ Scribed by C. Offidani; S. Strano Rossi; M. Chiarotti


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
234 KB
Volume
63
Category
Article
ISSN
0379-0738

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✦ Synopsis


This study investigates the distribution of some drugs in hair samples taken from different parts of the body (head, pubis and axillae). Samples drawn from 15 subjects who died from drug overdose were analysed. The concentrations of the drugs detected in the biological fluids did not appear to be correlated with those present in hair. The highest drug levels were observed in pubic hair. The concentration differences observed in the various types of hair can hypothetically be ascribed to a likely incorporation of the drugs from the outside.


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The concentrations of morphine and codeine were investigated in hair from the head, axillary and pubic regions obtained from 20 fatal heroin cases. Hair preparation involves decontamination procedure in dichloromethane at 37 degrees C for 15 min, solubilization in sodium hydroxide at 100 degrees C f