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Drug discovery approaches targeting the PI3K/Akt pathway in cancer

✍ Scribed by Garcia-Echeverria, C; Sellers, W R


Book ID
109970571
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
343 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract Fibroblast growth factor‐1 (FGF1), a prototypic member of the FGF family, is a potent angiogenic factor. Although FGF‐stimulated angiogenesis has been extensively studied, the molecular mechanisms regulating FGF1‐induced angiogenesis are poorly understood in vivo. Fumagillin, an antiang