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Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake

✍ Scribed by Alexandre Marin; Hao Sun; Ghaleb A Husseini; William G Pitt; Douglas A Christensen; Natalya Y Rapoport


Book ID
114161943
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
472 KB
Volume
84
Category
Article
ISSN
0168-3659

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The intracellular uptake and localization of a Β―uorescently labeled Pluronic P-105 in HL-60 leukemia cells and in A2780 drug-sensitive and A2780/ADR MDR ovarian carcinoma cells were characterized by Β―ow cytometry and Β―uorescence microscopy. Pluronic P-105 molecules were labeled with a pH-sensitive Β―