Drug Delivery

✍ Scribed by Vladimir P. Torchilin (auth.), Monika Schäfer-Korting (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2010
• Tongue: English
• Leaves: 449
• Series: Handbook of Experimental Pharmacology 197
• Edition: 1
• Category: Library

✦ Synopsis

In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

✦ Table of Contents

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Passive and Active Drug Targeting: Drug Delivery to Tumors as an Example....Pages 3-53
Nanoparticle Technologies for Cancer Therapy....Pages 55-86
Biosensing and Drug Delivery at the Microscale....Pages 87-112
Front Matter....Pages 113-113
Lipid Nanoparticles: Effect on Bioavailability and Pharmacokinetic Changes....Pages 115-141
Viral Vectors for Gene Transfer: Current Status of Gene Therapeutics....Pages 143-170
Pulmonary Drug Delivery: Medicines for Inhalation....Pages 171-192
Needle-Free Vaccine Injection....Pages 193-219
Pharmaceutically Used Polymers: Principles, Structures, and Applications of Pharmaceutical Delivery Systems....Pages 221-250
Mucoadhesive Drug Delivery Systems....Pages 251-266
Intrauterine Drug Delivery for Contraception and Gynaecological Treatment: Novel Approaches....Pages 267-298
Drug-Eluting Medical Implants....Pages 299-341
Front Matter....Pages 343-343
Improving Oral Delivery....Pages 345-398
Transdermal Drug Delivery....Pages 399-410
Targeting the Brain – Surmounting or Bypassing the Blood–Brain Barrier....Pages 411-431
Front Matter....Pages 433-433
Carriers in the Topical Treatment of Skin Disease....Pages 435-468
Medical Devices for the Treatment of Eye Diseases....Pages 469-489
Erratum to: Biosensing and Drug Delivery at the Microscale....Pages 501-501
Back Matter....Pages 491-500

✦ Subjects

Pharmacology/Toxicology; Pharmaceutical Sciences/Technology; Oncology; Dermatology; Neurology