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Drug brain distribution following intranasal administration of Huperzine A in situ gel in rats

✍ Scribed by Yan ZHAO; Peng YUE; Tao TAO; Qing-hua CHEN

Book ID
111355140
Publisher
Nature Publishing Group
Year
2007
Tongue
Chinese
Weight
505 KB
Volume
28
Category
Article
ISSN
1671-4083

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## Abstract The aim of this study was to investigate the pharmacokinetic behavior of huperzine A (Hup A) in plasma and cerebrospinal fluid (CSF) after intranasal administration (0.5 mg/kg) in male Sprague‐Dawley rats. A pharmacokinetic study of intravenous Hup A (0.5 mg/kg) was also performed. The