Drug abusers show impaired performance in a laboratory test of decision making

✍ Scribed by Steven Grant; Carlo Contoreggi; Edythe D London

• Book ID: 114073981
• Publisher: Elsevier Science
• Year: 2000
• Tongue: English
• Weight: 262 KB
• Volume: 38
• Category: Article
• ISSN: 0028-3932
• DOI: 10.1016/s0028-3932(99)00158-x

✦ Synopsis

A de®ning feature of drug addiction is persistent drug use despite long-term adverse consequences. This study examined the performance of drug abusers on a neuropsychological test that requires evaluation of long-term outcomes in the presence of a complex set of mixed reward/punishment contingencies (the Gambling Task). In order to control for generalized de®cits related to choice and planning, subjects were also administered the Wisconsin Card Sorting Task. Thirty polysubstance abusers were compared to a comparison group of 24 subjects who did not use illicit drugs of abuse. Drug abusers performed much more poorly on the Gambling Task (net score = 10.224.7, mean2s.e.m.) than controls (26.025.3), but did not dier from controls on the Wisconsin Card Sorting Task. The results show that drug abusers are more likely to make maladaptive decisions in the Gambling Task that result in long-term losses exceeding short-term gains. These ®ndings indicate that the Gambling Task may be a useful model in laboratory studies of cognitive dysfunctions associated with drug abuse. Published by Elsevier Science Ltd.