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Drosophila melanogaster as a model system for drug discovery and pathway screening

โœ Scribed by Sanjay Tickoo; Steven Russell


Book ID
117786568
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
72 KB
Volume
2
Category
Article
ISSN
1471-4892

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## Abstract Glioblastomas (GBM), the most common primary brain tumors, infiltrate the brain, grow rapidly, and are refractory to current therapies. Signature genetic lesions in glioblastomas include mutation of the epidermal growth factor receptor tyrosine kinase (EGFR) receptor tyrosine kinase and