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Droloxifene does not blunt bone anabolic effects of prostaglandin E2, but maintains prostaglandin E2-restored bone in aged, ovariectomized rats

โœ Scribed by H.Z Ke; D.T Crawford; H Qi; C.M Pirie; H.A Simmons; K.L Chidsey-Frink; H.K Chen; W.S.S Jee; D.D Thompson


Book ID
117808685
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
152 KB
Volume
24
Category
Article
ISSN
8756-3282

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Effects of long-term daily administratio
โœ Hua Zhu Ke; Webster S. S. Jee; Satoshi Mori; Xiao Jian Li; Donald B. Kimmel ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 869 KB

The effects of long-term prostaglandin E2 (PGE2) on cancellous bone in proximal tibial metaphysis were studied in 7-month-old male Sprague-Dawley rats given daily subcutaneous injections of 0, 1, 3, and 6 mg PGE2/kg/day and sacrificed after 60, 120, and 180 days. Histomorphometric analyses were perf