Symptomatic medical therapies for Parkinson's disease (PD) have been disease modifying and have led to improvement in daily function, quality of life, and survival. For 40 years, these therapies have been primarily dopaminergic, and currently include the dopamine (DA) precursor levodopa (LD), DA ago
Driving ability in Parkinson's disease: Current status of research
β Scribed by Ester I. Klimkeit; John L. Bradshaw; Judith Charlton; Rene Stolwyk; Nellie Georgiou-Karistianis
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 191 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0149-7634
No coin nor oath required. For personal study only.
β¦ Synopsis
Guidelines for assessing fitness to drive in individuals with neurodegenerative disorders, such as Parkinson's disease (PD), are subjective. It is therefore timely to review the current status of the literature not only for health professionals who are required to assess fitness to drive, but also for the development of future research directions. This review, in the context of PD, outlines the complex changes in driving behaviours, motor vehicle crash rates, driving simulator and on-road driving ability assessments, the relationship between disease severity, duration, medication dose and driving performance, the relationship between driving and neuropsychological test performance, and the effect of dopaminergic medications on driving. While it provides a current overview of the ongoing research, more comprehensive research is required for the full and proper development of policies and guidelines for assessing fitness to drive in PD.
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## Abstract This study evaluated selected clinical and functional tests as predictors of driving safety outcomes in Parkinson's disease (PD) patients. A total of 25 PD patients and 21 ageβmatched controls, all regular drivers, underwent neurological evaluation and assessment of cognitive, visual, a
## Abstract Clinical symptoms of Parkinson's disease (PD) can make driving hazardous. The removal of the privilege to drive reduces independence; nevertheless, to protect public safety, medical practitioners require reliable screening tools to decide whether a PD driver should be on the road. The a
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## Abstract Levodopa is the most effective symptomatic agent in the treatment of Parkinson's disease (PD) and the βgold standardβ against which new agents must be compared. However, there remain two areas of controversy: (1) whether levodopa is toxic, and (2) whether levodopa directly causes motor