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Driven translocation dynamics of polynucleotides through a nanopore: off-lattice Monte-Carlo simulations

✍ Scribed by C.-M. Chen

Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
430 KB
Volume
350
Category
Article
ISSN
0378-4371

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✦ Synopsis

The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

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