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Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate—a validated assay for the clinic

✍ Scribed by Gero P. Hooff; Roland J. W. Meesters; Jeroen J. A. van Kampen; Nick A. van Huizen; Birgit Koch; Asmar F. Y. Al Hadithy; Teun van Gelder; Albert D. M. E. Osterhaus; Rob A. Gruters; Theo M. Luider


Publisher
Springer
Year
2011
Tongue
English
Weight
434 KB
Volume
400
Category
Article
ISSN
1618-2650

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## Abstract An assay for the simultaneous analysis of pharmaceutical compounds and their metabolites from micro‐whole blood samples (__i.e__. 5 μL) was developed using an on‐line dried blood spot (on‐line DBS) device coupled with hydrophilic interaction/reversed‐phase (HILIC/RP) LC/MS/MS. Filter pa