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Dramatic increase in hepatic and biliary curcumin exposure by modulation of its elimination pathway in rats

✍ Scribed by Lee, Joo Hyun; Kim, Han Gyul; Oh, Ju-Hee; Lee, Young-Joo


Book ID
119876975
Publisher
Pharmaceutical Press
Year
2012
Tongue
English
Weight
430 KB
Volume
65
Category
Article
ISSN
2042-7158

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## Abstract The principal objectives of our study were to ascertain whether sulforaphane, at dietary levels of intake, modulates rat hepatic cytochrome P450 and phase II enzyme systems and to evaluate the impact of such changes in the chemopreventive activity of this isothiocyanate. Animals were ex