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DPB1*5901a: a novel HLA-DPB1 allele from a Caucasian family with insulin-dependent diabetes mellitus

✍ Scribed by J. A. Noble; A. S. Cavalli; H. A. Erlich


Book ID
115096615
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
310 KB
Volume
47
Category
Article
ISSN
0001-2815

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Both DQA1 and DQB1 genes are implicated
✍ D. A. Cavan; K. H. Jacobs; M. A. Penny; M. A. Kelly; C. Mijovic; D. Jenkins; J. πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 663 KB

Inherited susceptibility to Type 1 (insulin-dependent) diabetes mellitus is partly determined by HLA genes. It has been suggested that protection from disease may be conferred by HLA-DQB1 genes which encode molecules with aspartate at position 57. We investigated the contributions of HLA-DRB1, DQA1