We recently reported that drug-resistant prostate tumor cells (DU145, PC-3) are resistant to Fas-mediated killing by cytotoxic lymphocytes, and that this resistance can be overcome by treatment with subtoxic concentrations of chemotherapeutic drugs. Fas belongs to the tumor necrosis factor (TNF) fam
Doxorubicin sensitizes human bladder carcinoma cells to Fas-mediated cytotoxicity
โ Scribed by Youichi Mizutani; Yusaku Okada; Osamu Yoshida; Manabu Fukumoto; Benjamin Bonavida
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 366 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
RESULTS. The T24 human bladder carcinoma cell line constitutively expressed the
Fas on the cell surface; however, T24 line was resistant to anti-Fas MoAb. Treatment
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