Antitumor effect of adriamycin-encapsula
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Ki-Choon Choi; Je-Yong Bang; Chan Kim; Pyoung-Il Kim; Sang-Rak Lee; Wan-Tae Chun
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Article
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2009
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John Wiley and Sons
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English
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In this study, we prepared adriamycin (ADR)-encapsulated core-shell type nanoparticles of a poly(DL-lactide-co-glycolide) (PLGA) grafted-dextran (DexLG) copolymer and evaluated its antitumor activity in vitro and in vivo. The particle size of ADR-encapsulated DexLG nanoparticles was around 50-200 nm