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Doxorubicin-loaded PLGA nanoparticles by nanoprecipitation: preparation, characterization and in vitro evaluation

โœ Scribed by Betancourt, Tania; Brown, Brandon; Brannon-Peppas, Lisa


Book ID
115512544
Publisher
Future Medicine
Year
2007
Tongue
English
Weight
864 KB
Volume
2
Category
Article
ISSN
1743-5889

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Fabrication via a nonaqueous nanoprecipi
โœ Alessandro Dalpiaz; Eleonora Vighi; Barbara Pavan; Eliana Leo ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB

A novel nonaqueous nanoprecipitation method was proposed to achieve the encapsulation of a small weight hydrophilic drug (N(6)-cyclopentyladenosine, CPA) in PLGA nanoparticles using a mixture of cottonseed oil and Tween-80 as nonsolvent phase. The nanoparticles were characterized in vitro as concern