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Doxorubicin interacts directly with skinned single skeletal muscle fibres

✍ Scribed by Evert L. De Beer; Heather Finkle; Emile E. Voest; Bas G.V. Van Heijst; Piet Schiereck


Book ID
115887431
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
313 KB
Volume
214
Category
Article
ISSN
0014-2999

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Single fibres were isolated from the extensor digitorum longus (EDL) and the soleus (SOL) muscles of the hindlimb from young male Wistar rats which had undergone a 10-week programme of endurance swimming from the age of 2 weeks. Fibres were mechanically skinned and activated with Ca(2+)- and Sr(2+)-