Shell cross-linked and hepatocyte-target
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Changhai Lu; Malcolm M.Q. Xing; Wen Zhong
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Article
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2011
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Elsevier Science
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English
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Hepatocyte-targeting and shell cross-linked nanoparticles with lactose moiety on the surface and doxorubicin (DOX) in the core were prepared from lactose-PEG-DOX conjugate. The process consists of the synthesis of a novel ฮฑ-hydrazine-ฯ-propargyl poly(ethylene glycol) (PEG) with a double bond in the