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Doxorubicin activates apoptosis in primary neuronal cultures of rat cerebral cortex through p53-mediated pathways

โœ Scribed by M. Lopes; A. Meisel; F. Carvalho; M.L. Bastos


Book ID
116923342
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
82 KB
Volume
196
Category
Article
ISSN
0378-4274

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## Abstract Oxidative stress in the brain has been increasingly associated with the development of numerous human neurological diseases. Microglia, activated upon neuronal injury or inflammatory stimulation, are known to release superoxide anion (^ยท^O), hydrogen peroxide (H~2~O~2~), and nitric oxid