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Down's syndrome fibroblasts anticipate the accumulation of specific ageing-related mtDNA mutations

✍ Scribed by Roberto Del Bo; Giacomo Pietro Comi; Maria Paola Perini; Sandra Strazzer; Nereo Bresolin; Guglielmo Scarlato


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
170 KB
Volume
49
Category
Article
ISSN
0364-5134

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## Age-related decrease in the proportion of germinal center B cells from mouse Peyer's MRC, Laboratory of Molecular Biology, Cambridge patches is accompanied by an accumulation of somatic mutations in their immunoglobulin genes\* Somatic hypermutation of immunoglobulin genes and the generation of