Down's syndrome, Edwards' syndrome, Patau's syndrome —synthesis of glycosaminoglycans
✍ Scribed by Valery Kukharenko; Svetlana Sheleg; Mikhail Freudine; Elena Pichugina; Alexander Delvig
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 278 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0340-6717
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To the Editor: Trisomy 21 Down's syndrome (DS) predisposes to the development of acute lymphocytic and non-lymphocytic leukemias [ 1-31, acute myelofibrosis [4], and a transient myeloproliferative disorder of newborns [Z]. The hypereosinophilic syndrome (HES) is a myeloproliferative
Summary data are presented on 168 D/21 and 131 G/21 translocation trisomies reported to the New York State Chromosome Registry. By combining these data with others from the literature it is estimated that about 59% of D/21 cases are the result of mutation in hte parental generation; the rest are tra
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