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Down's syndrome births and pregnancy terminations in 1989 to 1993: preliminary findings

✍ Scribed by Eva Alberman; David Mutton; Roy Ide; Amanda Nicholson; Martin Bobrow


Book ID
111156802
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
250 KB
Volume
102
Category
Article
ISSN
1470-0328

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## Abstract ## BACKGROUND: The aim of this study was to examine trends of Down syndrome (DS) in relation to maternal age and termination of pregnancies (ToP) in 20 registries of the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR). ## METHODS: Trends of births wit

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We conducted a study to investigate the effect of parity on the following six serum markers used in screening for Down's syndrome, after adjusting them for ethnic group and maternal weight: alpha-fetoprotein (AFP), unconjugated oestriol (uE,), total human chorionic gonadotrophin (hCG), free a-hCG, f