Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells

Downregulation of the Rho GTPase signali

Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma

✍ Lu Jiang; Xiqiang Liu; Antonia Kolokythas; Jinsheng Yu; Anxun Wang; Caroline E. 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 464 KB

## Abstract Tumor metastasis is the dominant cause of death in cancer patients, including patients with oral tongue squamous cell carcinoma (TSCC). Previously, we reported that reduced miR‐138 level is correlated with enhanced metastatic potential in TSCC cells. Here, we demonstrate that miR‐138 su